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Prelude Cuts Q2 Losses and Costs 13%


Prelude Therapeutics (NASDAQ:PRLD), a clinical-stage precision oncology company concentrating on novel cancer therapies, released its second quarter 2025 earnings on August 14, 2025. The headline news was a GAAP net loss per share of $0.41. The company reported no revenue, in line with expectations. The quarter highlighted a large drop in operating expenses and a narrowed development focus, with management emphasizing a tighter cash runway and resource discipline as it advances its clinical pipeline. The period was characterized by a modestly improved loss, careful cost management, and a shrinking cash balance—supporting operations into the next year but underlining ongoing financial risk.

Source: Analyst estimates for the quarter provided by FactSet.

Pursuing new approaches in cancer drug development, Prelude Therapeutics is focused on discovering and developing new targeted therapies known as small molecule inhibitors and targeted protein degraders. These treatments are designed to address hard-to-treat cancers by targeting specific genetic drivers of disease. Most of its work takes place at the early and mid-clinical trial stage, meaning products are still years from reaching the market if successful.

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Source Fool.com

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